The second week of February 2016 was announced as Career Week in Copenhagen International School. Students had to find desirable place to working practice and contact to Workplace Supervisor. Chloe Wheeler choose Department of Biomedical Sciences of Copenhagen University and expressed a wish to spend a few days among staff and get an idea about the work in Medicine Institute.
In these two days staff talked to Chloe about the work here, demonstrated some of experiments and gave some general scientific information which could help Chloe to understand some basic mechanisms inside human bodies. Anastasiia Neganova gave talks about REVAMMAD project itself, her secondment in Berlin, collaboration between scientists and also about eye’s physiology and methods which help to investigate it.
Current week is the week of Erhvervspraktik for 9th grade students in Denmark when they get an experience of training in the place where they would like to continue their education/work. 15-years old Sofie Thorsen expressed the wish to spend this week working with Section of Renal and Vascular Research of Department of Biomedical Sciences (BMI) in Copenhagen University. Our group prepared intensive program for Sofie’s Erhvervspraktik. She attended experiment on rat’s kidney in our lab, experiment with myograph and got a general idea about modeling of blood vessels and vascular networks.
Anastasiia Neganova gave talks about basis of Laser speckle Imaging (LSI) technique, development of vascular networks, modelling of myogenic response gradient in microvascular networks, application of LSI technique to visualization of blood flow in the rat’s retina and chick’s chorioallantoic membrane. Anastasiia also gave the talk about REVAMMAD project when she explained the main goals of the project and the ways how it works.
In the end of Erhvervspraktik, Sofie shared her impressions about this experience: “I think it was very exciting to hear about the REVAMMAD project, what it was all about and what each person is working with. After the introduction to the project Anastasiia told me generally about the vascular networks. She also told me much more about her own work with modelling – especially the part about LSI and myogenic response I found very exciting. At first it was a bit difficult for me to understand all those new words in English which I didn´t even know in Danish. But Anastasiia explained it very well so I was able to understand most of it and I learned so many new and interesting things! Besides, Anastasiia answered all my questions about being a Ph.D. student as well. Being with Anastasiia and hearing all these things about the project and how it is to write a Ph.D. has definitely made me much more interested in scientific work and I think it would be very cool if I could have the opportunity to write a Ph.D. myself in the future“.
I was invited to give an internet talk at International Conference “Saratov Fall Meeting – 2014” (September 23–26, 2014), that was organized by N.G. Chernyshevsky Saratov State University. The main topics that are usually discussed at this conference are biophotonics and application of modern techniques and technologies in study of biological objects.
I presented actual results of my scientific work and gave a talk with title “The main aspects of mathematical modelling of retinal vessel network”.
Me and my supervisor Jens Christian Brings Jacobsen visited Neitherlands at 21th August to have a meeting with professor Ed Van Bavel who is working on mathematical modelling of vasculature.
We participated in unformal meeting in Academic Medical Center in Amsterdam. I presented actual results of my current work, we discussed perspective of our possible collaboration. Now, Ed Van Bavel is associate partner in the REVAMMAD network.
Second REVAMMAD Training Event was placed in Crete from June 8th to June 15th, 2014. We presented our progress, listened lectures on mashine learning, modelling and data analysis. We also visited Heraclion University.
As a part of collaboration, each of us prepared the 30 min. talk with other ESR on choosen topic. Me and Piotr Chudzik prepared the presentation on “Adaptive Responses: Vessel Tone”. It brought us to work together on conceptual topic, what is always useful for young scientist.
First REVAMMAD training event was placed in Lincoln Univensity from November 24th to December 6th, 2013. It was good experience and opportunity to create unique network of young scientists, who interested in research of the retina.
Very rich 2 week program included lectures on modelling, retinal physiology and diseases, as well as image analysis. Additionally, all ESRs presented themselves and their projects. From my point of view, even if you have a particular speciality it’s good to get to know something beyond the scope of your subject of inquiry.
Moreover, we have some unformal group events, where we could socialize, discuss our work and plan possible collaborations. All ESRs and PLs visited York and at the last days, together, developed the logo for REVAMMAD project.
My name is Anastasiia Neganova, I’ve defended my Master of Science thesis in Saratov State University (Russia) in 2012. My scientific background is biophysics and optics. Now I’m ESR 1.3 within REVAMMAD Project and my project title is “Modeling retinal arteriolar vasomotion”. I’m working on my PhD thesis in Copenhagen University under Jens Christian Brings Jacobsen supervision since October 2013.
I’ve decided to participate in REVAMMAD project because today cardiovascular diseases (CVDs) are ” the number one cause of death globally” (according Global status report on noncommunicable diseases 2010. Geneva, World Health Organization, 2011) and retina is really amazing subject of inquiry for investigation of different vascular mechanisms (that allow vessels auto regulate their diameter according permanently changing demands) and blood flow under normal or pathological conditions. Moreover, such educational program, which is aimed to train young scientists and help them to create new scientific communities is a great opportunity for each of us.
Main goals of my PhD:
1) Construction of a new improved macroscopic model of the vascular network
2) Assigning vascular properties characteristic for retinal vessels and construction of a virtual retinal network
3) Application of the network models to estimate hemodynamic and functional parameters
4) Simulation of arterial vasomotion in retinal networks
Copenhagen University Campus